Nicotine preloading may be beneficial for smoking cessation
نویسندگان
چکیده
منابع مشابه
Nicotine patch preloading for smoking cessation (the preloading trial): study protocol for a randomized controlled trial
BACKGROUND The use of nicotine replacement therapy before quitting smoking is called nicotine preloading. Standard smoking cessation protocols suggest commencing nicotine replacement therapy only on the first day of quitting smoking (quit day) aiming to reduce withdrawal symptoms and craving. However, other, more successful smoking cessation pharmacotherapies are used prior to the quit day as w...
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Cigarette smoking is the leading cause of preventable disease and death in the world. Smoking was responsible for an estimated 100 million deaths in the 20 century, and is expected to cause 10 times that number in the current century. A recent study estimated that smoking accounted for 16.6% of all deaths in Canada in 2002 – a total of 37,209 deaths. The direct and indirect costs of smoking in ...
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BACKGROUND Mecamylamine is a nicotine antagonist (that is it blocks the effect of nicotine). The rationale for its use in smoking cessation is that it may block the rewarding effect of nicotine and thus reduce the urge to smoke. OBJECTIVES The objective of this review was to determine the effectiveness of mecamylamine in promoting smoking cessation, either alone or in combination with nicotin...
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1. James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-8. 2. Tefferi A. Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1. Leukemia 2010;24:1128-38. 3. Harrison C, Kiladjian J-J, Al-Ali HK, et al. JAK inhibition ...
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BACKGROUND The aim of nicotine replacement therapy (NRT) is to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence. OBJECTIVES The aims of this review were: To determine the effect of NRT compared to placebo in aiding smoking cessation, and to consider ...
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ژورنال
عنوان ژورنال: Pharmacy Today
سال: 2018
ISSN: 1042-0991
DOI: 10.1016/j.ptdy.2018.08.006